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Coenzyme Q10 May Help Treat Male Infertility, According to StudyInfertility is a devastating blow for couples trying to conceive. Unfortunately, this condition is all too common. Couples are usually considered to be infertile if they have been unable to conceive after one year of unprotected intercourse or when a woman fails to carry a pregnancy to full term. Factors that may cause infertility can include abnormal reproductive systems, anomalies of organs in proximity to reproductive areas, infections, endocrine dysfunction (including hypothyroidism), and emotional stress. Pharmaceutical drugs, substance abuse, certain pesticides and environmental estrogens, and tobacco use can also cause infertility. When medical treatment is sought, physicians use diagnostic tests and physical examinations to determine whether the condition is present in either or both partners. They then determine an appropriate treatment strategy. According to a new study, physicians may want to add CoQ10 to their treatment of infertile men who have a condition known as idiopathic asthenozoospermia—the loss or reduction of sperm motility in semen. The pilot study, which appeared in the January Fertility and Sterility, examined the effects of CoQ10 on 22 men, age 25 to 39, with idiopathic asthenozoospermia. In the six-month study, the subjects consumed 200 mg of CoQ10 twice daily. After treatment, CoQ10 levels significantly increased in seminal plasma. In addition, CoQ10 levels in sperm cells significantly increased. Furthermore, phosphatidylcholine levels rose significantly in both seminal plasma and sperm cells. Sperm forward motility also increased after CoQ10 treatment, from nine percent at baseline to 16 percent after treatment. Other improvements in the male’s sperm also were noted after treatment. Six months after the CoQ10 treatment stopped, sperm forward motility was significantly reduced from 16 percent back to 9.5 percent. Three of the women whose male partners participated in the study became pregnant within three months after the CoQ10 administration ended. The study’s authors concluded that CoQ10 can improve a condition that leads to male infertility. The exogenous administration of CoQ(10) may play a positive role in the treatment of asthenozoospermia, the researchers wrote. This is probably the result of its role in mitochondrial bioenergetics and its antioxidant properties. Reference Balercia G, Mosca F, Mantero F, Boscaro M, Mancini A, Ricciardo-Lamonica G, Littarru G. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril. |
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